The folks at sc2mapster.com have created the first custom map with a custom editor called Milky Way editor, which was created by examining the API. The following is footage of the first custom map in StarCraft II, a rudimentary tower defense map created without the yet-to-be-released Galaxy Map Editor:
There is even a preliminary API documentation for Galaxy containing the list of functions that we will see once the editor is released. Check out sc2mapster.com, which is sure to be an excellent modding website for StarCraft II.